If you’re looking for a skin-boosting treatment that works with your body—not against it—PRF (Platelet-Rich Fibrin) and ezGel offer a completely natural way to restore skin quality, soften fine lines, and brighten tired areas like under the eyes. These regenerative treatments are derived from growth factors in your blood and used to stimulate collagen, improve circulation, and support skin healing at a cellular level.
At Little Laser Clinic in Long Island City, every injectable treatment is performed by Christine Chen, PA-C, who has more than a decade of experience in dermatology and aesthetics. Her approach is precise, conservative, and always customized to your skin. Whether you’re targeting dark circles, early volume loss, or a general need to “reset” your skin, PRF and ezGel offer subtle, meaningful improvements with zero foreign substances.
100% natural—no synthetic ingredients
Improves texture, tone, and skin elasticity
Great for under-eye hollows, fine lines, and crepey skin
Minimal swelling or downtime, usually resolves in 1–2 days
Long-lasting results with collagen stimulation over time
PRF stands for Platelet-Rich Fibrin, a regenerative injectable derived from your own blood. It’s similar to PRP (Platelet-Rich Plasma) but with a few key differences: PRF contains more white blood cells and fibrin and releases growth factors more slowly, giving your skin longer access to its regenerative benefits.
The process starts with a simple blood draw. Your sample is then spun at a low speed in a centrifuge to isolate the healing components—platelets, white blood cells, and stem cells—without the need for additives or anticoagulants. This golden concentrate is then reinjected into areas of concern to stimulate healing and collagen production. Clients love PRF because it’s gentle, natural, and versatile. We often use it under the eyes, around the mouth, in acne-scarred areas, or even on the scalp to support hair restoration.
What Is ezGel and How Is It Different?
ezGel is an enhanced version of PRF that combines your natural growth factors with your body’s own albumin, creating a thicker, gel-like consistency for more volume and hydration.
While traditional PRF is ideal for skin quality and brightness, ezGel is perfect when a little support is needed—like softening smile lines, plumping under-eye hollows, or improving overall structure without synthetic filler. It’s especially popular with patients who want subtle volume without the risk of filler migration or a “done” look.
At Little Laser Clinic, ezGel is often combined with PRF or other treatments to further personalize results. Christine Chen, PA-C, will advise you on the best version for your goals.
After a consultation with Christine Chen, PA-C, we’ll begin with a quick blood draw and spin your sample in a centrifuge. Once the PRF is ready, we apply topical numbing to ensure comfort during the injection process. The injections take 15–30 minutes, depending on the treatment area.
Because PRF is derived from your own body, it’s well-tolerated. You may notice a slight swelling or tenderness right after treatment, especially under the eyes, but this usually subsides within 24–48 hours.
PRF is ideal for clients looking to correct early signs of aging or repair skin that’s lost some of its resilience. Common concerns it treats include:
PRF is safe for all skin types and is perfect for clients looking for a more holistic approach to skin rejuvenation.
PRF encourages your body to improve skin from within, using your own healing cells to:
Because it doesn’t contain synthetic material, PRF is an excellent option for those who prefer low-intervention, biocompatible treatments.
PRF is a good option for healthy adults who want to treat early aging or texture issues with a natural approach. It’s especially popular among clients in their 30s and 40s who notice early under-eye hollows, fine lines, or tired-looking skin.
You should avoid PRF if you have a blood clotting disorder, active infection in the treatment area, or are currently pregnant or breastfeeding. Christine will review your complete medical history to ensure this treatment is safe and appropriate for you.
After a PRF treatment, you might notice swelling, light bruising, or small injection-site bumps. These typically resolve within 1–2 days. We advise avoiding alcohol, exercise, or heat exposure for 24 hours to minimize swelling and optimize healing.
Most clients notice visible improvements after 2–3 sessions, spaced about a month apart. Results build gradually over time as collagen and elastin production increase.
PRF (platelet-rich fibrin) injections offer a subtle, regenerative approach to skin rejuvenation by using your body’s own growth factors to stimulate collagen, improve elasticity, and enhance overall skin tone. Results develop gradually, with most patients noticing firmer, smoother, more radiant skin over the course of several weeks. Because PRF works with your body’s natural healing process, the improvements are soft and natural—less about dramatic change and more about refreshed, healthier-looking skin.
Many clients benefit from a series of treatments spaced about a month apart. Stacked treatments promote lasting improvements in fine lines, crepiness, and skin resilience for a radiant, rejuvenated look.
At Little Laser Clinic, PRF (platelet-rich fibrin) treatments are medically guided, carefully curated procedures designed to work in harmony with your skin. Performed by Christine Chen, PA-C, a dermatology-trained provider with over a decade of experience, every PRF session is approached with precision and clinical insight. Whether you’re using PRF to improve under-eye hollows, soften fine lines, or enhance hair restoration, we tailor the protocol to your goals, skin condition, and long-term plan.
PRF relies on your body’s own healing power, and our role is to apply that potential with thoughtful technique, safety, and strategy. With a strong understanding of skin anatomy, aging patterns, and combination therapies, we ensure your treatment fits seamlessly into a bigger picture of subtle, sustained rejuvenation.
PRF contains more fibrin and white blood cells than PRP, which allows it to release growth factors over a longer period. This often leads to better, longer-lasting skin rejuvenation.
Not exactly. ezGel creates a volumizing effect using your body’s own proteins and growth factors. It doesn’t contain hyaluronic acid or synthetic materials like traditional fillers.
Most people benefit from a series of 2–3 sessions spaced a month apart. Christine may adjust your schedule based on your skin's needs and how you respond to the first treatment.
Yes. PRF uses your own blood, so the risk of allergy or rejection is extremely low. It’s one of the safest injectable treatments available.
Results can last 6–12 months, depending on the treatment area and your body’s natural collagen-building ability.
Most clients find the treatment very tolerable. We apply a topical anesthetic beforehand to reduce discomfort during injections.
Absolutely. PRF is one of our favorite under-eye treatments—it’s gentle and natural and can improve both darkness and skin thickness.
Yes. PRF and ezGel are non-inflammatory and safe for skin of color, making them ideal choices for clients across the Fitzpatrick scale.
PRF uses your own blood components, while Rejuran uses purified salmon DNA to regenerate skin. Both improve texture and collagen but through different biological mechanisms.
Yes, PRF and ezGel pair beautifully with microneedling, laser, or even dermal fillers to create a customized plan that addresses texture, tone, and volume at the same time.