Rejuran
Chronic redness, enlarged pores, or fine lines that don’t seem to budge with skincare alone? These subtle yet stubborn issues often point to deeper concerns like inflammation, collagen loss, or skin barrier damage. Rejuran is a regenerative treatment designed to address exactly that. By introducing polynucleotides (PN)—the building blocks of DNA—into the skin, Rejuran promotes healing from within, helping restore balance, hydration, and elasticity over time.
At Little Laser Clinic, we specialize in advanced injectable treatments that blend science and aesthetics. Christine Chen, PA-C, brings over a decade of dermatology and aesthetic experience to every Rejuran session. With an expert understanding of skin biology and a highly personalized approach, she crafts every treatment plan to meet your skin’s specific needs. Schedule a consultation to find out if Rejuran is the right choice for you.
Injectable skin booster that stimulates collagen and tissue repair for healthier, smoother skin
Often used on the face, neck, under eyes, or acne-scarred areas
Suitable for all skin types, including skin of color
Minimal downtime with pinpoint redness or swelling lasting 1–2 days
Gradual improvement over 4–6 weeks with peak results at 3 months
Rejuran is a regenerative skin injectable derived from polynucleotides (PN), molecules that help repair and rebuild tissue. Originally developed in South Korea, Rejuran is widely known as the “salmon DNA” treatment—though it’s purified and highly biocompatible, meaning it works harmoniously with human tissue.
Unlike hyaluronic acid fillers or neuromodulators like Botox, Rejuran doesn’t add volume or pause muscle movement. Instead, it encourages your skin to function more efficiently by supporting cell turnover, collagen production, and anti-inflammatory effects. The result is skin that looks and behaves like a younger, healthier version of itself.
At Little Laser Clinic, we may recommend Rejuran alone or in combination with other treatments like microneedling or laser treatments for enhanced collagen remodeling and skin renewal.
Rejuran is administered through a series of microinjections across the treatment area. Numbing cream is applied beforehand for comfort. The entire process typically takes about 30 minutes. Christine Chen, PA-C, performs all Rejuran injections herself, using her dermatology background to assess your skin in detail and place the product exactly where it’s most needed.
You may see small bumps immediately after treatment, which typically settle within a few hours. Mild redness or swelling may persist for a day or two. Most clients return to normal activities within 24 hours.
Rejuran offers a unique approach to skin rejuvenation by helping your skin heal itself from within. Benefits include:
Because the results are subtle and gradual, this treatment is ideal for clients seeking a natural improvement without a dramatic change.
Rejuran is ideal for treating skin that’s lost its balance—whether due to aging, inflammation, or previous damage. It's particularly well-suited for:
Rejuran is safe for all skin tones and works well for clients with skin of color, which is an area of focus at Little Laser Clinic.
If your skin feels tired, sensitive, or like it’s not responding to your usual skincare routine, Rejuran may help reset its baseline health. This treatment is especially useful for clients in their 30s to 50s looking to address early signs of aging, poor skin quality, or acne scarring. It’s also excellent for clients with darker skin tones or sensitive skin, as the formulation is non-inflammatory and gentle.
You should avoid Rejuran if you’re pregnant, breastfeeding, or have a history of severe allergies to fish products. Christine Chen, PA-C, will discuss your health history in detail before moving forward.
Rejuran Recovery
There’s little to no downtime after Rejuran. Some clients experience mild swelling or redness that resolves within 1–2 days. Small injection bumps may appear immediately after treatment but typically settle within hours. To maximize results, we recommend avoiding alcohol, strenuous workouts, and heat-based treatments (like saunas or lasers) for 24–48 hours.
Most patients see noticeable improvements in tone and texture after 2–3 sessions spaced about a month apart, with results continuing to improve for several months.
Rejuran Results
Rejuran is about building skin quality from the inside out. Most clients begin to see improved texture and hydration within 2–4 weeks, with fuller benefits appearing after 6–12 weeks. Results are cumulative and can last 6 months or longer, depending on your skin condition, age, and treatment plan.
To maintain results, Christine may suggest maintenance treatments 2–3 times per year.
Christine Chen, PA-C, brings over a decade of dermatology experience into every treatment session. Her training in medical and cosmetic dermatology gives her an edge in customizing Rejuran for patients with sensitive or complex skin concerns, including those with skin of color or chronic conditions like acne or redness.
At Little Laser Clinic, we’re deeply committed to personalized care. We don’t just offer Rejuran—we offer Rejuran treatments that are right for your skin. You’ll never find a one-size-fits-all approach here. Just thoughtful, expert treatments that fit you.
No. While fillers add volume, Rejuran is a skin booster that enhances the quality and function of your skin. It helps repair tissue and stimulate collagen without changing your facial contours.
Most clients benefit from 3 sessions spaced about 4 weeks apart. Christine will recommend a plan based on your skin’s needs and response after the first session.
Yes. Rejuran pairs well with microneedling, RF microneedling, and certain lasers to boost collagen stimulation and improve texture and tone more dramatically.
Yes. Rejuran is non-inflammatory and has no melanin-disrupting effects, making it safe and effective for skin of color across the Fitzpatrick scale.
While all three are regenerative injectables, Rejuran uses purified polynucleotides from salmon DNA, whereas PRF and ezGel are derived from your own blood. Christine can help you determine which is best based on your goals and skin condition.
You may notice smoother skin texture and improved hydration in a few weeks, with more dramatic collagen improvement after 6–12 weeks.
A topical numbing cream is applied before treatment, and most clients experience only mild discomfort during the injections.
Yes. Rejuran is often used to soften acne scars by improving skin texture and boosting collagen. It works best when combined with microneedling or RF treatments.
No. It can also be used on the neck, décolletage, or hands to improve thin or damaged skin.
Avoid touching your face, wearing makeup for 12–24 hours, and any heat, alcohol, or strenuous exercise for 1–2 days after your session.
